How to spend one day in Florence and make the most of it? Florence, or Firenze as the Italians call it, is known as the cradle of the Renaissance. So it is no secret that this city has a lot of architectural treasures to offer. With so many sights to see, it seems impossible to explore this city in one day and I’m going to be honest with you; it is! But if you do decide to do a day trip to Florence, then I have the perfect one day itinerary for you!